Use este identificador para citar ou linkar para este item: http://bibliotecadigital.anvisa.gov.br/jspui/handle/anvisa/1669
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dc.rights.licenseEscolha o acesso:::ACESSO ABERTO (CC BY-NC-ND 4.0) - A Regulação Autoral da Biblioteca Digital da Anvisa permite o reconhecimento da produção intelectual como sendo de acesso aberto, adotando-se assim, a Creative Commons Attribution-NonCommercial-NonDerivates 4.0 International. Concedendo a outros que realizem o download e compartilhamento da produção intelectual desde que atribuam crédito ao autor, mas sem que possam alterá-los de nenhuma forma ou utilizá-los para fins comerciais.pt_BR
dc.contributor.authorSilva, Ricardo E. da-
dc.contributor.authorAmato, Angélica A.-
dc.contributor.authorGuilhem, Dirce B.-
dc.contributor.authorCarvalho, Marta R. de-
dc.contributor.authorNovaes, Maria R. C. G.-
dc.date.accessioned2022-09-05T20:38:29Z-
dc.date.available2022-09-05T20:38:29Z-
dc.date.issued2018-01-
dc.identifier.issn1663-9812-
dc.identifier.urihttp://bibliotecadigital.anvisa.ibict.br/jspui/handle/anvisa/1669-
dc.description.abstractIntroduction: Although international health research involves some benefits for the host countries, such as access to innovative treatments, the research itself may not be aligned with their communities’ actual health needs. Objective: To map the global landscape of clinical trials run in Latin American and Caribbean countries and discuss the addressing of local health needs in the agenda of international clinical trials. Methods: The present study is a cross-sectional overview and used data referent to studies registered between 01/01/2014 and 12/31/2014 in the World Health Organization’s (WHO) International Clinical Trials Registry Platform (ICTRP). Results: Non-communicable diseases such as diabetes, cancer, and asthma—studies which were financed mainly by industries—were the conditions investigated most in the region of Latin America and the Caribbean. The neglected diseases, on the other hand, such as Chagas disease, and dengue, made up 1% of the total number of studies. Hospitals and nonprofit nongovernmental organizations prioritize resources for investigating new drugs for neglected diseases, such as Chagas disease and dengue. Conclusion: The international multicenter clinical trials for investigating new drugs are aligned with the health needs of the region of Latin America and the Caribbean, when one considers the burden resulting from the non-communicable diseases in this region. However, the transmissible diseases, such as tuberculosis and AIDS, and the neglected diseases, such as Chagas disease and dengue, which have an important impact on public health in this region, continue to arouse little interest among the institutions which finance the clinical trials.pt_BR
dc.language.isoenpt_BR
dc.titleInternational clinical trials in Latin American and Caribbean countries : research and development to meet local health needspt_BR
dc.typeArtigopt_BR
dc.rights.holderRicardo E. da Silvapt_BR
dc.rights.holderAngélica A. Amatopt_BR
dc.rights.holderDirce B. Guilhempt_BR
dc.rights.holderMarta R. de Carvalhopt_BR
dc.rights.holderMaria R. C. G. Novaespt_BR
dc.identifier.doihttps://doi.org/10.3389/fphar.2017.00961-
dc.local[Lausanne]pt_BR
dc.description.physical8 p.pt_BR
dc.description.additionalReceived: 08 September 2017 -- Accepted: 18 December 2017 -- Published: 05 January 2018pt_BR
dc.description.additionalComo citar: SILVA, Ricardo E. da et al. International clinical trials in Latin American and Caribbean Countries: research and development to meet local health needs. Frontiers in Pharmacology, [Lausanne], v. 8, artigo 961, January 2018. DOI 10.3389/fphar.2017.00961. Disponível em: https://www.frontiersin.org/articles/10.3389/fphar.2017.00961/full. Acesso em: 5 set. 2022.pt_BR
dc.subject.keywordClinical trialspt_BR
dc.subject.keywordDrugspt_BR
dc.subject.keywordNoncommunicable diseasespt_BR
dc.subject.keywordNeglected diseasespt_BR
dc.subject.keywordLatin America and the Caribbeanpt_BR
dc.subject.keywordENSAIOS CLÍNICOSpt_BR
dc.subject.keywordDrogaspt_BR
dc.subject.keywordDoenças não comunicáveispt_BR
dc.subject.keywordDoenças negligenciadaspt_BR
dc.subject.keywordAmérica Latinapt_BR
dc.subject.keywordCaribept_BR
dc.rights.accessAcesso Abertopt_BR
dc.itemdestaqueNãopt_BR
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